{"id":214,"date":"2026-08-17T09:27:56","date_gmt":"2026-08-17T08:27:56","guid":{"rendered":"https:\/\/schools.stem.open.ac.uk\/environment-earth-ecosystem-sciences\/?page_id=214"},"modified":"2026-08-17T09:35:55","modified_gmt":"2026-08-17T08:35:55","slug":"astrobiology-laboratories","status":"publish","type":"page","link":"https:\/\/schools.stem.open.ac.uk\/environment-earth-and-ecosystem-sciences\/research\/analytical-facilities\/astrobiology-laboratories\/","title":{"rendered":"Astrobiology Laboratories"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">Astrobiology Laboratories<\/h4>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"wp-block-paragraph\">The astrobiology facilities are furnished with standard equipment used to isolate and culture aerobic microorganisms; microbiological safety cabinets, autoclaves, microscopes, and an incubator room.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">What makes these laboratories stand out are our anaerobic microbiology capabilities. We have a gas purging station for creating anaerobic growth media, a separate dedicated anaerobic gas mix for charging Wheaton tube headspace, and both Don Whitley and Coy anaerobic chambers for inoculating and sub-culturing anaerobic microorganisms.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Our most recent addition to the laboratories is a series of MicrobeMeters used to determine the optical density of anaerobic microorganisms in-situ.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/university.open.ac.uk\/stem\/environment-earth-ecosystem-sciences\/sites\/www.open.ac.uk.stem.environment-earth-ecosystem-sciences\/files\/images\/astrobiology-facilities.jpg\" alt=\"Microbiological safety cabinets with gloves\"\/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Molecular Biology Laboratories<\/h4>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Many samples analysed in the Astrobiology Laboratories originate from extreme environments across the world. Extracting  nucleic acids from these habitats takes patience and a great deal of method development.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">To prevent cross-contamination our facilities separate out nucleic acid extraction, PCR preparation and PCR into three distinct areas.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Coming soon: a facility dedicated to extracting nucleic acid from low-biomass environments.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Equipment of interest includes:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>FastPrep24 and FastPrep24 5G homogenisers;<\/li>\n\n\n\n<li>SpeedVac SPD130 vacuum concentrator;<\/li>\n\n\n\n<li>Qiagen\u2019s BLU-V system;<\/li>\n\n\n\n<li>Various PCR machines including gradient PCR;<\/li>\n\n\n\n<li>QuantStudio 3 real-time qPCR machine;<\/li>\n\n\n\n<li>NanoDrop One<sup>TM&nbsp;<\/sup>UV-Vis spectrophotometer;<\/li>\n\n\n\n<li>Qubit<sup>TM<\/sup>&nbsp;2 fluorometer;<\/li>\n\n\n\n<li>Gel Doc HR+ gel documentation system;<\/li>\n\n\n\n<li>Invitrogen\u2122 Novex\u2122 WedgeWell\u2122 protein electrophoresis system.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">If you have any questions or want to find out more about our Astrobiology and Molecular Biology Facilities, please contact:&nbsp;<a href=\"https:\/\/stem.open.ac.uk\/people\/cg8474\">Ceri Gwyther.<\/a><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/university.open.ac.uk\/stem\/environment-earth-ecosystem-sciences\/sites\/www.open.ac.uk.stem.environment-earth-ecosystem-sciences\/files\/images\/Molecular-Biology-Laboratories.jpg\" alt=\"Results of a molecular biology experiment - grey horizontal bars on a black background\"\/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Environmental simulation chambers<\/h4>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8f761849 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"wp-block-paragraph\">Environmental simulation chambers are used to reproduce, as far as possible, the near- and sub-surface environments of Mars and the icy moons of Europa and Enceladus.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The continuous flow-through reactors allow researchers to sample the chemistry and\/or the microbiology of these systems under a range of different temperatures and pressures.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We currently have four reactors, the specifications of which can be found below.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/university.open.ac.uk\/stem\/environment-earth-ecosystem-sciences\/sites\/www.open.ac.uk.stem.environment-earth-ecosystem-sciences\/files\/images\/Environmental-simulation-chambers%20.jpg\" alt=\"Various size valves on a workbench\"\/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><th class=\"has-text-align-left\" data-align=\"left\">Environmental simulation chamber<\/th><th class=\"has-text-align-left\" data-align=\"left\">Chamber volume (ml)<\/th><th class=\"has-text-align-left\" data-align=\"left\">Temperature range (\u00b0C)<\/th><th class=\"has-text-align-left\" data-align=\"left\">Pressure range (bar)<\/th><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">MSS<\/td><td class=\"has-text-align-left\" data-align=\"left\">300<\/td><td class=\"has-text-align-left\" data-align=\"left\">Ambient to 350<\/td><td class=\"has-text-align-left\" data-align=\"left\">Atmosphere to 50<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">IM<\/td><td class=\"has-text-align-left\" data-align=\"left\">600<\/td><td class=\"has-text-align-left\" data-align=\"left\">-10 to 150<\/td><td class=\"has-text-align-left\" data-align=\"left\">Atmosphere to 100<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">Chamber 3<\/td><td class=\"has-text-align-left\" data-align=\"left\">600<\/td><td class=\"has-text-align-left\" data-align=\"left\">-10 to 150<\/td><td class=\"has-text-align-left\" data-align=\"left\">Atmosphere to 100<\/td><\/tr><tr><td class=\"has-text-align-left\" data-align=\"left\">Chamber 4<\/td><td class=\"has-text-align-left\" data-align=\"left\">600<\/td><td class=\"has-text-align-left\" data-align=\"left\">-10 to 150<\/td><td class=\"has-text-align-left\" data-align=\"left\">Atmosphere to 100<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Alongside the continuous flow-through reactors, we have a range of static reactors which are used to analyse the chemistry of various regolith compositions and water-rock interactions.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Haskel air intensifiers are used to increase the pressure achievable from a standard 200bar gas cylinder to a high 345bar, which would be the equivalent of simulating the pressures at a depth of 3.5km beneath the surface of Mars.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Finally, in this facility we have a Swagelok gas mixing station for bespoke gas mix make up for use in the simulated environmental chambers.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you have any questions or want to find out more about our Environmental Simulation Chambers, please contact:&nbsp;<a href=\"https:\/\/stem.open.ac.uk\/people\/dnj27\">David Johnson.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Astrobiology Laboratories The astrobiology facilities are furnished with standard equipment used to isolate and culture aerobic microorganisms; microbiological safety cabinets, autoclaves, microscopes, and an incubator room. What makes these laboratories stand out are our anaerobic microbiology capabilities. We have a gas purging station for creating anaerobic growth media, a separate dedicated anaerobic gas mix for [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":0,"parent":75,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_unity_review_frequency":"","_unity_review_next_due":0,"_unity_review_reset_requested":false,"footnotes":""},"class_list":["post-214","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/schools.stem.open.ac.uk\/environment-earth-and-ecosystem-sciences\/wp-json\/wp\/v2\/pages\/214","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/schools.stem.open.ac.uk\/environment-earth-and-ecosystem-sciences\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/schools.stem.open.ac.uk\/environment-earth-and-ecosystem-sciences\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/schools.stem.open.ac.uk\/environment-earth-and-ecosystem-sciences\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/schools.stem.open.ac.uk\/environment-earth-and-ecosystem-sciences\/wp-json\/wp\/v2\/comments?post=214"}],"version-history":[{"count":1,"href":"https:\/\/schools.stem.open.ac.uk\/environment-earth-and-ecosystem-sciences\/wp-json\/wp\/v2\/pages\/214\/revisions"}],"predecessor-version":[{"id":215,"href":"https:\/\/schools.stem.open.ac.uk\/environment-earth-and-ecosystem-sciences\/wp-json\/wp\/v2\/pages\/214\/revisions\/215"}],"up":[{"embeddable":true,"href":"https:\/\/schools.stem.open.ac.uk\/environment-earth-and-ecosystem-sciences\/wp-json\/wp\/v2\/pages\/75"}],"wp:attachment":[{"href":"https:\/\/schools.stem.open.ac.uk\/environment-earth-and-ecosystem-sciences\/wp-json\/wp\/v2\/media?parent=214"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}